Hydroxocobalamin and sodium thiosulfate interfere negatively with measurement of creatine kinase activity.

نویسندگان

  • J L Beaudeux
  • F Flourie
  • J Peynet
  • E Magny
  • F Rousselet
چکیده

2120 CLINICAL CHEMISTRY, Vol. 40, No. 11, 1994 we reported here, we overcome this problem by using the filters. We have not observed any late-eluting peaks that would interfere with the subsequent chromatogram nor any reduction in column life attributable to sample contamination. Moreover, the results we obtained with the amperometric detector are comparable with those of the coulometric detector.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Hydroxocobalamin versus sodium thiosulfate for the treatment of acute cyanide toxicity in a swine (Sus scrofa) model.

STUDY OBJECTIVE We compare the efficacy of hydroxocobalamin to sodium thiosulfate to reverse the depressive effects on mean arterial pressure in a swine model of acute cyanide toxicity and gain a better understanding of the mechanism of action of the hydroxocobalamin in reversal of the toxicity. METHODS Swine were intubated, anesthetized, and instrumented with central arterial and venous line...

متن کامل

Sodium thiosulfate or hydroxocobalamin for the empiric treatment of cyanide poisoning?

Cyanide poisoning must be seriously considered in victims of smoke inhalation from enclosed space fires; it is also a credible terrorism threat agent. The treatment of cyanide poisoning is empiric because laboratory confirmation can take hours or days. Empiric treatment requires a safe and effective antidote that can be rapidly administered by either out-of-hospital or emergency department pers...

متن کامل

Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event

Cyanide is rapidly reacting and causes arrest of aerobic metabolism. The symptoms are diffuse and lethal and require high clinical suspicion. Remediation of symptoms and mortality is highly dependent on quick treatment with a cyanide antidote. Presently, there are two widely accepted antidotes: sodium thiosulfate and hydroxocobalamin. These treatments act on different components of cyanide's me...

متن کامل

In Vitro Inhibition of Human Sperm Creatine Kinase by Nicotine, Cotinine and Cadmium, as a Mechanism in Smoker Men Infertility

Background Nicotine, cotinine and cadmium are harmful components of cigarettes that have an effect on human reproductive function. Although the effects of cigarette smoke on male reproductive function is characterized in several articles its mechanism of action is still unknown. In the present study, we investigate the effect of nicotine, cotinine and cadmium on human sperm creatine kinase acti...

متن کامل

Hydroxocobalamin and sodium thiosulfate versus sodium nitrite and sodium thiosulfate in acute cyanide toxicity.

5. Villanova FE, Andrade E, Leal E, et al. Erection induced by Tx2-6 toxin of Phoneutria nigriventer spider: expression profile of genes in the nitric oxide pathway of penile tissue of mice. Toxicon. 2009; 54:793-801. 6. Winkel KD, Tibballs J, Molenaar P, et al. Cardiovascular actions of the venom from the Irukandji (Carukia barnesi) jellyfish: effects in human, rat and guinea-pig tissues in vi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Clinical chemistry

دوره 40 11 Pt 1  شماره 

صفحات  -

تاریخ انتشار 1994